Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 8/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22892432 | 0.90 | MME (0.53) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL22892480 | 0.90 | MME (0.53) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL28706003 | 0.90 | MME (0.53) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL30544885 | 0.90 | MME (0.44) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL30617861 | 0.83 | CTSD (0.44) | MMEACECPA1ACE2 | |
| SCHEMBL29155528 | 0.83 | ALDH1A1 (0.51) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL29155527 | 0.83 | ALDH1A1 (0.51) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL29566998 | 0.82 | ALDH1A1 (0.47) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL11656501 | 0.82 | ALDH1A1 (0.50) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL11656504 | 0.82 | ALDH1A1 (0.50) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12178878-B2 | Amyloid peptide scaffolds coordinate with Alzheimer's disease drugs | THE UNIVERSITY OF MASSACHUSETTS (US) | 2024-12-31 | — | — | US | disclosed |
| US-20240197893-A1 | Amyloid Peptide Scaffolds Coordinate with Alzheimer's Disease Drugs | THE TEXAS A&M UNIVERSITY SYSTEM | 2024-06-20 | — | — | US | disclosed |
| US-20240175879-A1 | METHOD FOR ASSESSING EFFICACY OF TREATMENT PROTOCOLS FOR NEURODEGENERATIVE DISEASES | EM Scientific Limited (GB) | 2024-05-30 | — | — | US | disclosed |