SCHEMBL30925414

SCHEMBL30925414

O=S(=O)(Nc1cccc2c(F)ccnc12)c1ccc(C(F)(F)F)nc1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC40A1 Q9NP59 16/20 0.69
▸ GLO1 Q04760 3/20 0.48
▸ CKS1B P61024 1/20 0.45
▸ SKP2 Q13309 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214236 1.00 SLC40A1 (0.69) SLC40A1GLO1CKS1BSKP2MEN1
SCHEMBL30925403 0.87 SLC40A1 (0.67) SLC40A1CKS1BSKP2MEN1KMT2A
SCHEMBL30925464 0.84 SLC40A1 (0.70) SLC40A1GLO1CKS1BSKP2MEN1
SCHEMBL11973285 0.81 SLC40A1 (1.00) SLC40A1GLO1CKS1BSKP2MEN1
SCHEMBL30925471 0.81 SLC40A1 (1.00) SLC40A1GLO1CKS1BSKP2MEN1
SCHEMBL11995655 0.81 SLC40A1 (1.00) SLC40A1CKS1BSKP2MEN1KMT2A
SCHEMBL11995653 0.74 SLC40A1 (0.77) SLC40A1GLO1CKS1BSKP2
SCHEMBL16235491 0.74 SLC40A1 (0.69) SLC40A1GLO1MEN1KMT2A
SCHEMBL27214189 0.72 SLC40A1 (0.57) SLC40A1GLO1CKS1BSKP2MEN1
SCHEMBL11973361 0.72 SLC40A1 (1.00) SLC40A1GLO1CKS1BSKP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 SLC40A1 3357/4885GLO1 3779/4885CKS1B 2287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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