SCHEMBL30925536

SCHEMBL30925536

Cc1ccc(S(=O)(=O)Nc2cccc3cc(F)cnc23)nc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SLC40A1 Q9NP59 15/20 0.70
▸ KMT2A Q03164 3/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ CKS1B P61024 2/20 0.48
▸ SKP2 Q13309 2/20 0.48
▸ AGTR1 P30556 2/20 0.48
▸ OPRK1 P41145 2/20 0.48
▸ MITF O75030 1/20 0.48
▸ S1PR4 O95977 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ S1PR1 P21453 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ GLO1 Q04760 2/20 0.47
▸ MEN1 O00255 2/20 0.46
▸ NFKBIA P25963 1/20 0.45
▸ RELA Q04206 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214164 1.00 SLC40A1 (0.70) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL27214306 0.90 SLC40A1 (0.77) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL30925568 0.90 SLC40A1 (0.77) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL30553559 0.86 SLC40A1 (0.74) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL26964196 0.86 SLC40A1 (0.74) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL30925487 0.86 SLC40A1 (0.70) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL30925553 0.84 SLC40A1 (0.67) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL11973663 0.83 SLC40A1 (1.00) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL30925548 0.78 SLC40A1 (0.77) SLC40A1KMT2ATDP1CKS1BSKP2
SCHEMBL30925528 0.78 SLC40A1 (0.73) SLC40A1TDP1AGTR1HTTGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 SLC40A1 3357/4885KMT2A 1323/4885TDP1 4247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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