SCHEMBL30925556

SCHEMBL30925556

O=S(=O)(Nc1c(Cl)ccc2cccnc12)c1ncccc1Cl

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC40A1 Q9NP59 15/20 0.71
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214293 1.00 SLC40A1 (0.71) SLC40A1MEN1KMT2AATM
SCHEMBL30925412 0.89 SLC40A1 (0.68) SLC40A1MEN1KMT2AATM
SCHEMBL26964306 0.89 SLC40A1 (0.68) SLC40A1MEN1KMT2AATM
SCHEMBL30553458 0.89 SLC40A1 (0.68) SLC40A1MEN1KMT2AATM
SCHEMBL26964309 0.88 SLC40A1 (0.67) SLC40A1
SCHEMBL26964166 0.86 SLC40A1 (0.64) SLC40A1MEN1KMT2AATM
SCHEMBL27214276 0.86 SLC40A1 (0.64) SLC40A1MEN1KMT2AATM
SCHEMBL30925405 0.85 SLC40A1 (0.62) SLC40A1MEN1KMT2A
SCHEMBL29801049 0.85 SLC40A1 (0.62) SLC40A1MEN1KMT2AATM
SCHEMBL26964177 0.85 SLC40A1 (0.62) SLC40A1MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 SLC40A1 3357/4885MEN1 2604/4885KMT2A 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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