Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214257 | 1.00 | SCN9A (0.52) | SCN9ASLC40A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL30925406 | 0.81 | SLC40A1 (0.48) | SCN9ASLC40A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27214253 | 0.81 | SLC40A1 (0.48) | SCN9ASLC40A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30925412 | 0.76 | SLC40A1 (0.68) | SLC40A1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL27214195 | 0.75 | SLC40A1 (0.47) | SLC40A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL30925573 | 0.75 | SLC40A1 (0.47) | SLC40A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL30925398 | 0.74 | SLC40A1 (0.51) | SLC40A1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL30925456 | 0.74 | SLC40A1 (0.72) | SLC40A1SMN1; SMN2KDM4EHPGDMEN1 | |
| SCHEMBL27214322 | 0.74 | SLC40A1 (0.72) | SLC40A1SMN1; SMN2KDM4EHPGDMEN1 | |
| SCHEMBL30925535 | 0.71 | SLC40A1 (0.73) | SLC40A1MEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ZOETIS LLC | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ARSA, MRPS2, SULT2A1 | SCN9A 432/4885SLC40A1 3357/4885L3MBTL1 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.