SCHEMBL30925581

SCHEMBL30925581

COc1ccc2cccnc2c1NS(=O)(=O)c1ncccc1C1CC1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC40A1 Q9NP59 8/20 0.63
▸ ALDH1A1 P00352 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ TSHR P16473 1/20 0.44
▸ MEN1 O00255 4/20 0.43
▸ KMT2A Q03164 4/20 0.43
▸ AGTR1 P30556 1/20 0.43
▸ GHSR Q92847 2/20 0.41
▸ GLO1 Q04760 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214298 1.00 SLC40A1 (0.63) SLC40A1ALDH1A1POLBTSHRMEN1
SCHEMBL26964227 0.84 SLC40A1 (0.61) SLC40A1MEN1KMT2A
SCHEMBL30925399 0.79 SLC40A1 (0.58) SLC40A1ALDH1A1MEN1KMT2AAGTR1
SCHEMBL27214174 0.79 SLC40A1 (0.58) SLC40A1ALDH1A1MEN1KMT2AAGTR1
SCHEMBL30925398 0.78 SLC40A1 (0.51) SLC40A1ALDH1A1MEN1KMT2AAGTR1
SCHEMBL11973715 0.77 SLC40A1 (1.00) SLC40A1ALDH1A1POLBMEN1KMT2A
SCHEMBL27214305 0.74 SLC40A1 (0.49) SLC40A1ALDH1A1POLBTSHRMEN1
SCHEMBL27214314 0.73 SLC40A1 (0.65) SLC40A1ALDH1A1POLBTSHRMEN1
SCHEMBL30925454 0.70 SLC40A1 (0.61) SLC40A1ALDH1A1POLBTSHRMEN1
SCHEMBL26964313 0.70 SLC40A1 (0.61) SLC40A1ALDH1A1POLBTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 SLC40A1 3357/4885ALDH1A1 1470/4885POLB 3189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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