Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 19/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 18/20 | 0.42 |
| ▸ | PDE1A | P54750 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428068 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL8554027 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL21449327 | 0.67 | PDE1B (0.44) | PDE1CPDE1BPDE1A | |
| SCHEMBL30928708 | 0.65 | NPC1 (0.35) | — | |
| SCHEMBL19301731 | 0.64 | PDE1B (0.60) | PDE1CPDE1BPDE1A | |
| SCHEMBL5254451 | 0.63 | ALDH1A1 (0.42) | — | |
| SCHEMBL18488318 | 0.62 | DRD2 (0.53) | — | |
| Dioxane SCHEMBL4259401 | 0.61 | MAPK1 (0.32) | — | |
| SCHEMBL22498772 | 0.61 | SPHK1 (0.34) | — | |
| SCHEMBL23566057 | 0.61 | PDE1A (0.50) | PDE1CPDE1BPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626423-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |