Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180096 | 1.00 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9491573 | 0.88 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30926569 | 0.86 | MEN1 (1.00) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9489593 | 0.86 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL5250030 | 0.86 | MEN1 (1.00) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9491786 | 0.86 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9491005 | 0.83 | ALDH1A1 (0.73) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL13985217 | 0.80 | TDP1 (0.75) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL5474178 | 0.77 | POLB (0.73) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL13985123 | 0.77 | HSD17B10 (0.80) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | ALDH1A1 1085/4885POLB 4136/4885MAPT 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.