Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491573 | 0.88 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL27180096 | 0.86 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30926569 | 0.86 | MEN1 (1.00) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL5250030 | 0.86 | MEN1 (1.00) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30926480 | 0.86 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9491786 | 0.86 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9491005 | 0.83 | ALDH1A1 (0.73) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL6800614 | 0.81 | MMP2 (0.64) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL13985217 | 0.80 | TDP1 (0.75) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL5474178 | 0.77 | POLB (0.73) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |