Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30926348 | 0.88 | ALDH1A1 (0.44) | KDM4EMAPTHPGDRECQL | |
| SCHEMBL23148885 | 0.87 | KDM4E (0.40) | KDM4EGPR119HPGDEPHX1 | |
| SCHEMBL14829908 | 0.77 | KDM4E (0.49) | KDM4EMAPTTHRBGPR119HPGD | |
| SCHEMBL4477598 | 0.77 | KDM4E (0.52) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL30926233 | 0.76 | PTPN11 (0.50) | MAPTGPR119 | |
| SCHEMBL23459591 | 0.76 | GPR119 (0.57) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL31665288 | 0.76 | KDM4E (0.45) | KDM4EMAPTTHRBGPR119HPGD | |
| SCHEMBL3060679 | 0.76 | KDM4E (0.48) | KDM4EMAPTTHRBGPR119HPGD | |
| SCHEMBL26450489 | 0.75 | GPR119 (0.53) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL3897024 | 0.74 | KDM4E (0.52) | KDM4EMAPTTHRBGPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626423-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |