Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181133 | 1.00 | SIRT2 (0.69) | SIRT2SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL27179454 | 0.92 | SIRT2 (0.80) | SIRT2SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL30926944 | 0.92 | SIRT2 (0.80) | SIRT2SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL30926499 | 0.82 | LMNA (0.76) | SIRT2SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL27179489 | 0.82 | LMNA (0.76) | SIRT2SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL15953979 | 0.81 | SIRT2 (1.00) | SIRT2SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL27180071 | 0.81 | SIRT2 (0.71) | SIRT2SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL30926898 | 0.81 | SIRT2 (0.71) | SIRT2SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL27181375 | 0.81 | SMN1; SMN2 (0.63) | SIRT2SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL27180894 | 0.81 | MEN1 (0.74) | SMN1; SMN2MEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | SIRT2 1335/4885SMN1; SMN2 3468/4885GAA 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.