Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179454 | 1.00 | SIRT2 (0.80) | SIRT2SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL27181133 | 0.92 | SIRT2 (0.69) | SIRT2SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL30926555 | 0.92 | SIRT2 (0.69) | SIRT2SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL15953979 | 0.89 | SIRT2 (1.00) | SIRT2SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL30926499 | 0.87 | LMNA (0.76) | SIRT2SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL27179489 | 0.87 | LMNA (0.76) | SIRT2SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL27181378 | 0.87 | ALDH1A1 (0.85) | SIRT2SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL27179416 | 0.87 | SIRT2 (0.84) | SIRT2SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL15953760 | 0.86 | SIRT2 (0.93) | SIRT2SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL15952977 | 0.86 | SIRT2 (0.90) | SIRT2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | SIRT2 1335/4885SMN1; SMN2 3468/4885GAA 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.