Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552324 | 0.81 | KDM4E (0.56) | KDM4EGLAMAPTPOLBL3MBTL1 | |
| SCHEMBL1340684 | 0.79 | MAPT (0.51) | KDM4EMAPTPOLBHTTNPC1 | |
| SCHEMBL7078523 | 0.79 | CA12 (0.43) | KDM4EGLAMAPTPOLBHTT | |
| SCHEMBL3084781 | 0.79 | HPGD (0.62) | KDM4EMAPTPOLBHTTHPGD | |
| SCHEMBL79936 | 0.79 | KDM4E (0.68) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL29560778 | 0.79 | KDM4E (0.68) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL24450657 | 0.78 | KEAP1 (0.61) | KDM4EMAPTPOLBCES2ALDH1A1 | |
| SCHEMBL2081024 | 0.78 | RECQL (0.53) | KDM4EGLAALOX15ALDH1A1KMT2A | |
| SCHEMBL24147311 | 0.78 | KDM4E (0.52) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL22552676 | 0.78 | KDM4E (0.52) | KDM4EGLAALDH1A1MYCNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626423-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |