Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560778 | 1.00 | KDM4E (0.68) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL1189192 | 0.83 | KDM4E (0.52) | KDM4EGLAMAPTPOLBPLAU | |
| Hydrochloric Acid SCHEMBL856910 | 0.82 | KDM4E (0.50) | KDM4EGLAMAPTPOLBPLAU | |
| Methyl Alcohol SCHEMBL29017641 | 0.82 | KDM4E (0.66) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL23118725 | 0.81 | KDM4E (0.59) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL29622752 | 0.81 | KDM4E (1.00) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL145485 | 0.81 | KDM4E (1.00) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL147774 | 0.81 | KDM4E (0.70) | KDM4EGLAMAPTPOLBPLAU | |
| SCHEMBL30864269 | 0.80 | MAOA (0.53) | KDM4EGLAMAPTPOLBHTT | |
| SCHEMBL11575664 | 0.80 | KDM4E (0.58) | KDM4EGLAMAPTPOLBPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119012730-B | All-inorganic perovskite solar cell based on 2-amino-5-bromoacetophenone interface modification and preparation method thereof | 中国计量大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119012730-A | All-inorganic perovskite solar cell based on 2-amino-5-bromoacetophenone interface modification and preparation method thereof | 中国计量大学 | 2024-11-22 | — | — | CN | claimed |
| US-8003784-B2 | Cyanopyrrole containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same | WYETH LLC (US) | 2011-08-23 | — | — | US | claimed |
| US-20090306371-A1 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | WYETH (US) | 2009-12-10 | — | — | US | claimed |
| EP-1756095-B1 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | WYETH CORP (US) | 2008-05-21 | — | — | EP | claimed |
| EP-1756095-A2 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | Wyeth (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005105739-A2 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | WYETH (US) | 2005-11-10 | — | — | WO | claimed |
| US-20050239779-A1 | Cyanopyrrole-containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same | WYETH (US) | 2005-10-27 | — | — | US | claimed |
| US-12528796-B2 | Modulators of RAS GTPase | TOSK, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20260008767-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-31 | — | — | US | disclosed |
| US-20250230169-A1 | Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety | CURIS INC (US) | 2025-07-17 | — | — | US | disclosed |
| EP-4574210-A2 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | The Scripps Research Institute (US) | 2025-06-25 | — | — | EP | disclosed |
| CN-119012730-B | All-inorganic perovskite solar cell based on 2-amino-5-bromoacetophenone interface modification and preparation method thereof | 中国计量大学 | 2025-06-13 | — | — | CN | disclosed |
| WO-2004000801-A2 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | WYETH (US) | 2003-12-31 | — | — | WO | disclosed |
| WO-2004000230-A2 | CYCLOTHIOCARBAMATIVE DERIVATIVES AS PR MODULATORS AND USE THEREOF FOR TREATMENT OF SKIN DISORDERS | WYETH (US) | 2003-12-31 | — | — | WO | disclosed |
| US-5214059-A | Dermatitis, psoriasis | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-05-25 | — | — | US | disclosed |
| US-5166170-A | 2-(AMINOARYL) INDOLES AND INDOLINES AS TOPICAL ANTIINFLAMMATORY AGENTS FOR THE TREATMENT OF SKIN DISORDERS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0406734-A2 | 2-(Aminoaryl)indoles and indolines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |
| US-3987047-A | ANORETICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239779-A1 | Cyanopyrrole-containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same | CBR3, MMAB, CTH | KDM4E 398/4885GLA 2728/4885MAPT 4585/4885 |
| US-20250230169-A1 | Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety | BAZ2A, BAZ2B, PI4KB | KDM4E 868/4885GLA 2443/4885MAPT 3887/4885 |
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | ADORA2B, ADORA2A, ADORA1 | KDM4E 3478/4885GLA 4261/4885MAPT 4767/4885 |
| US-20090306371-A1 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | CBR3, CTH, MMAB | KDM4E 385/4885GLA 2793/4885MAPT 4590/4885 |
| US-20260008767-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR3, SSTR2 | KDM4E 4278/4885GLA 2436/4885MAPT 4671/4885 |
| US-12528796-B2 | Modulators of RAS GTPase | KRAS, NRAS, HRAS | KDM4E 3816/4885GLA 1571/4885MAPT 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.