Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179771 | 1.00 | ALDH1A1 (0.62) | ALDH1A1LMNAITGA1POLBMEN1 | |
| SCHEMBL27180776 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAITGA1POLBMEN1 | |
| SCHEMBL30926434 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAITGA1POLBMEN1 | |
| SCHEMBL30926878 | 0.84 | LMNA (0.82) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL27181000 | 0.84 | LMNA (0.82) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL27179881 | 0.83 | KMT2A (0.66) | ALDH1A1LMNAITGA1MEN1KMT2A | |
| SCHEMBL30926771 | 0.83 | KMT2A (0.66) | ALDH1A1LMNAITGA1MEN1KMT2A | |
| SCHEMBL30926965 | 0.83 | RXFP1 (0.56) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL27179671 | 0.83 | RXFP1 (0.56) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL27180067 | 0.81 | SMN1; SMN2 (0.66) | ALDH1A1LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | ALDH1A1 1085/4885LMNA 4774/4885ITGA1 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.