Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179757 | 1.00 | LMNA (0.69) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27180114 | 0.85 | MAPT (0.69) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27179730 | 0.85 | MAPT (0.72) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27180063 | 0.83 | MEN1 (0.82) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27180787 | 0.83 | MEN1 (0.67) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27179777 | 0.83 | MAPT (0.67) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27180446 | 0.83 | MEN1 (0.62) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16620958 | 0.83 | RAB9A (1.00) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30926692 | 0.76 | MAPT (0.85) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27181452 | 0.76 | MAPT (0.85) | LMNAMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | LMNA 4774/4885MAPT 4236/4885SMN1; SMN2 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.