Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 15/20 | 0.71 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181559 | 1.00 | GPR27 (0.71) | GPR27AVPR2TDP1CYP19A1NPC1 | |
| SCHEMBL27181433 | 0.92 | CYP19A1 (0.60) | GPR27AVPR2TDP1CYP19A1MEN1 | |
| SCHEMBL30926996 | 0.92 | CYP19A1 (0.60) | GPR27AVPR2TDP1CYP19A1MEN1 | |
| SCHEMBL27180941 | 0.79 | KMT2A (0.67) | GPR27AVPR2NPC1RAB9AMEN1 | |
| SCHEMBL30926774 | 0.79 | KCNK3 (0.60) | GPR27AVPR2CYP19A1 | |
| SCHEMBL27180429 | 0.79 | KCNK3 (0.60) | GPR27AVPR2CYP19A1 | |
| SCHEMBL30926705 | 0.78 | KMT2A (0.70) | GPR27AVPR2CYP19A1NPC1RAB9A | |
| SCHEMBL27179849 | 0.78 | KMT2A (0.70) | GPR27AVPR2CYP19A1NPC1RAB9A | |
| SCHEMBL30926865 | 0.76 | GPR27 (0.61) | GPR27AVPR2CYP19A1MEN1KMT2A | |
| SCHEMBL27180015 | 0.76 | GPR27 (0.61) | GPR27AVPR2CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | GPR27 4269/4885AVPR2 4623/4885TDP1 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.