Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 11/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180015 | 1.00 | GPR27 (0.61) | GPR27CYP19A1AVPR2ADORA3ADORA2A | |
| SCHEMBL31610103 | 0.81 | MAPK1 (0.67) | GPR27AVPR2MAPK1MAPTMEN1 | |
| SCHEMBL12597643 | 0.80 | IDH1 (0.67) | GPR27AVPR2MAPTIDH1MEN1 | |
| SCHEMBL491680 | 0.80 | SLC10A6 (0.60) | GPR27AVPR2ADORA3ADORA2AADORA2B | |
| SCHEMBL30926705 | 0.77 | KMT2A (0.70) | GPR27CYP19A1AVPR2MAPTMEN1 | |
| SCHEMBL27179849 | 0.77 | KMT2A (0.70) | GPR27CYP19A1AVPR2MAPTMEN1 | |
| SCHEMBL30926996 | 0.77 | CYP19A1 (0.60) | GPR27CYP19A1AVPR2MAPTMEN1 | |
| SCHEMBL27181433 | 0.77 | CYP19A1 (0.60) | GPR27CYP19A1AVPR2MAPTMEN1 | |
| SCHEMBL30927072 | 0.76 | GPR27 (0.71) | GPR27CYP19A1AVPR2MEN1KMT2A | |
| SCHEMBL27181559 | 0.76 | GPR27 (0.71) | GPR27CYP19A1AVPR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | GPR27 4269/4885CYP19A1 1283/4885AVPR2 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.