Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 6/20 | 0.56 |
| ▸ | JAK1 | P23458 | 3/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | PRKX | P51817 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24656050 | 0.79 | NUDT1 (0.59) | NUDT1JAK1EGLN2JAK3PDPK1 | |
| SCHEMBL13465776 | 0.78 | NUDT1 (0.58) | NUDT1JAK1EGLN2JAK3PDPK1 | |
| SCHEMBL3300546 | 0.76 | NUDT1 (0.57) | NUDT1JAK1EGLN2JAK3KDM4E | |
| SCHEMBL2773330 | 0.76 | NUDT1 (0.57) | NUDT1JAK1EGLN2JAK3PDPK1 | |
| SCHEMBL27038245 | 0.76 | NUDT1 (0.56) | NUDT1JAK1EGLN2JAK3PDPK1 | |
| SCHEMBL45713 | 0.76 | NUDT1 (0.56) | NUDT1JAK1EGLN2JAK3PDPK1 | |
| SCHEMBL543601 | 0.76 | EGLN2 (0.47) | NUDT1JAK1EGLN2ALDH1A1AHR | |
| SCHEMBL3200526 | 0.73 | NUDT1 (0.76) | NUDT1JAK1EGLN2JAK3KDM4E | |
| SCHEMBL2144054 | 0.72 | NUDT1 (1.00) | NUDT1JAK1EGLN2JAK3PDPK1 | |
| SCHEMBL13449511 | 0.72 | NUDT1 (0.51) | NUDT1JAK1EGLN2JAK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924272-A | Synthesis method and application of JAK inhibitor drug intermediate | 珠海联邦制药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |