Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.55 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.49 |
| ▸ | QPCT | Q16769 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956581 | 0.91 | CYP17A1 (0.54) | CYP19A1CYP3A4MAPTCYP11B1CYP11B2 | |
| SCHEMBL27956579 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP2D6CYP11B1CYP11B2 | |
| SCHEMBL27956540 | 0.84 | CYP19A1 (0.56) | CYP19A1POLBCYP11B1CYP11B2 | |
| SCHEMBL27956564 | 0.84 | HMOX1 (0.59) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27709549 | 0.83 | CYP19A1 (0.52) | CYP19A1POLBCYP11B1CYP11B2 | |
| SCHEMBL27956569 | 0.82 | CYP19A1 (0.47) | CYP19A1CYP1A2CYP3A4MAPTCYP11B1 | |
| SCHEMBL10652258 | 0.81 | CYP19A1 (0.69) | CYP19A1HMOX2TBXAS1QPCTCYP1A2 | |
| SCHEMBL28947592 | 0.81 | CYP19A1 (0.55) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11737828 | 0.80 | CYP19A1 (0.51) | CYP19A1HMOX2TBXAS1QPCTCYP1A2 | |
| SCHEMBL11737831 | 0.80 | CYP19A1 (0.51) | CYP19A1HMOX2TBXAS1QPCTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |