Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956564 | 0.85 | HMOX1 (0.59) | CYP19A1CYP11B1CYP11B2IDO1HMOX1 | |
| SCHEMBL27956579 | 0.85 | CYP19A1 (0.53) | CYP19A1CYP11B1CYP11B2IDO1 | |
| SCHEMBL30928337 | 0.84 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2POLB | |
| SCHEMBL28811703 | 0.84 | IDO1 (0.49) | CYP19A1CYP11B1CYP11B2IDO1HMOX1 | |
| SCHEMBL27956581 | 0.82 | CYP17A1 (0.54) | CYP19A1CYP11B1CYP11B2IDO1HMOX1 | |
| SCHEMBL27956569 | 0.82 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL28947592 | 0.81 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL9374363 | 0.80 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2IDO1HMOX1 | |
| SCHEMBL7562437 | 0.78 | CYP19A1 (0.72) | CYP19A1HMOX1 | |
| SCHEMBL6299999 | 0.78 | CYP19A1 (0.72) | CYP19A1HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724271-A | Substituted imidazole-1-ethylene compound and application thereof | LUWAN BRANCH RUI JIN HOSPITAL SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE | 2014-04-16 | — | — | CN | disclosed |