Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476149 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL7656600 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL15563887 | 0.79 | DAO (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2DAO | |
| SCHEMBL7833852 | 0.79 | HPGD (0.53) | ALDH1A1MEN1KMT2ANPSR1HTT | |
| SCHEMBL15563837 | 0.79 | GRIA1 (0.49) | ALDH1A1MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL16968255 | 0.78 | DAO (0.54) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL15563840 | 0.78 | DAO (0.54) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL15564177 | 0.76 | CNR1 (0.50) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL15564226 | 0.75 | CNR1 (0.56) | ALDH1A1KMT2ANPSR1LMNASMN1; SMN2 | |
| SCHEMBL7368621 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184594-A | Preparation method of aza-uracil compound, and compound prepared by same and application of aza-uracil compound | 杭州医学院 | 2024-06-14 | — | — | CN | disclosed |