Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12400717 | 0.81 | ADORA2B (0.48) | ALDH1A1ADORA3MEN1KMT2APDE4A | |
| SCHEMBL30928935 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAGAACASP3NR1H3 | |
| SCHEMBL15563887 | 0.75 | DAO (0.49) | ALDH1A1ADORA3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28113645 | 0.75 | HTR2C (0.43) | ALDH1A1ADORA3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7833852 | 0.75 | HPGD (0.53) | ALDH1A1GAAMEN1KMT2ADAO | |
| SCHEMBL15563837 | 0.75 | GRIA1 (0.49) | ALDH1A1ADORA3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4965760 | 0.75 | ADORA2B (0.48) | ALDH1A1NR1H3MEN1KMT2AADORA2A | |
| SCHEMBL16968255 | 0.74 | DAO (0.54) | ALDH1A1ADORA3LMNANR1H3MEN1 | |
| SCHEMBL15563840 | 0.74 | DAO (0.54) | ALDH1A1ADORA3LMNAMEN1KMT2A | |
| SCHEMBL28113124 | 0.73 | HPGD (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |