Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25104099 | 1.00 | MAPKAPK2 (0.50) | MAPKAPK2RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10314189 | 0.84 | MAPKAPK2 (0.38) | MAPKAPK2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3668795 | 0.80 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM3 | |
| SCHEMBL2797793 | 0.80 | LMNA (0.48) | RAB9ACYP1A2 | |
| SCHEMBL2481660 | 0.80 | SLC6A4 (0.37) | MAPKAPK2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL14417237 | 0.79 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM3 | |
| SCHEMBL4066264 | 0.78 | TSHR (0.45) | RAB9ASLC6A4TSHRCYP1A2 | |
| SCHEMBL27884240 | 0.78 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL4716012 | 0.76 | MBTPS1 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM3 | |
| SCHEMBL14498227 | 0.76 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395892-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |