Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929423 | 0.87 | BRD4 (0.44) | BRD4KAT2BBRD9F2F7 | |
| SCHEMBL30929440 | 0.82 | F2 (0.43) | F2F7F3P2RX7PREP | |
| SCHEMBL30929457 | 0.82 | BRD4 (0.50) | BRD4BRD9F2F7F3 | |
| SCHEMBL30929433 | 0.81 | F2 (0.49) | F2F7F3P2RX7 | |
| SCHEMBL30929399 | 0.81 | F2 (0.47) | BRD4KAT2BBRD9F2F7 | |
| Ammonia Solution, Strong SCHEMBL30929419 | 0.81 | BRD4 (0.49) | BRD4BRD9F2F7F3 | |
| SCHEMBL30929452 | 0.78 | F2 (0.45) | BRD4KAT2BBRD9F2F7 | |
| SCHEMBL30929451 | 0.77 | F2 (0.44) | BRD4KAT2BBRD9F2F7 | |
| SCHEMBL30929475 | 0.77 | F2 (0.46) | BRD4BRD9F2F7F3 | |
| SCHEMBL12914550 | 0.76 | RAB9A (0.44) | F2F7F3BCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |