Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929457 | 0.85 | BRD4 (0.50) | PREPF2F7F3BRD4 | |
| Ammonia Solution, Strong SCHEMBL30929419 | 0.85 | BRD4 (0.49) | PREPF2F7F3BRD4 | |
| SCHEMBL30929475 | 0.82 | F2 (0.46) | PREPF2F7F3BRD4 | |
| SCHEMBL30929449 | 0.81 | F2 (0.47) | F2F7F3 | |
| SCHEMBL30929399 | 0.79 | F2 (0.47) | PREPF2F7F3BRD4 | |
| SCHEMBL30929465 | 0.78 | PREP (0.44) | PREPF2F7F3P2RX7 | |
| SCHEMBL30929451 | 0.77 | F2 (0.44) | PREPF2F7F3BRD4 | |
| SCHEMBL30929452 | 0.76 | F2 (0.45) | PREPF2F7F3BRD4 | |
| SCHEMBL30929431 | 0.75 | BRD4 (0.48) | PREPF2F7F3BRD4 | |
| SCHEMBL30929440 | 0.74 | F2 (0.43) | PREPF2F7F3KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |