Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929716 | 0.90 | HDAC6 (0.39) | HDAC6CTSKHDAC1HDAC2HDAC3 | |
| SCHEMBL30315135 | 0.81 | HDAC6 (0.36) | HDAC6CTSKHDAC1HDAC2 | |
| SCHEMBL28089582 | 0.81 | HDAC6 (0.42) | HDAC6CTSKHDAC1HDAC2HDAC3 | |
| SCHEMBL1446179 | 0.73 | HDAC6 (0.38) | HDAC6CTSKHDAC1HDAC2 | |
| SCHEMBL10260946 | 0.72 | HDAC6 (0.40) | HDAC6CTSKHDAC1HDAC2 | |
| SCHEMBL15085762 | 0.72 | HDAC6 (0.40) | HDAC6CTSKHDAC1HDAC2 | |
| SCHEMBL30314910 | 0.72 | HDAC6 (0.35) | HDAC6HDAC1HDAC2 | |
| SCHEMBL30314894 | 0.71 | HDAC6 (0.34) | HDAC6HDAC1HDAC2 | |
| SCHEMBL3161486 | 0.70 | HDAC6 (0.39) | HDAC6CTSKHDAC1HDAC2 | |
| SCHEMBL20663951 | 0.70 | CTSK (0.33) | HDAC6CTSKHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103370-A | Fused tetracyclic quinazoline derivatives as ERBB2 inhibitors | 英莱汶公司 | 2024-05-28 | — | — | CN | disclosed |