SCHEMBL30929969

SCHEMBL30929969

COC(=O)c1cccc(COc2ccc3cc(-c4ccc5ccccc5c4)ccc3c2-c2c(OCc3cccc(C(=O)OC)c3)ccc3cc(-c4ccc5ccccc5c4)ccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 12/20 0.51
PLAU P00749 2/20 0.47
ERN1 O75460 1/20 0.47
NPC1 O15118 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
XBP1 P17861 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.45
CYSLTR1 Q9Y271 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30929975 0.95 MRGPRX4 (0.56) MRGPRX4PLAUERN1
SCHEMBL30929974 0.91 PLAU (0.47) PLAUERN1NPC1MAPTRAB9A
SCHEMBL30929966 0.90 MRGPRX4 (0.58) MRGPRX4NPC1GAAMAPTXBP1
SCHEMBL30929964 0.89 MAPT (0.49) PLAUNPC1MAPTRAB9ASMN1; SMN2
SCHEMBL30929972 0.86 SMPD1 (0.49) MRGPRX4PLAUERN1MAPTRAB9A
SCHEMBL30929976 0.83 SMPD1 (0.54) MRGPRX4NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL32684052 0.81 MAPT (0.46) MRGPRX4NPC1GAAMAPTRAB9A
SCHEMBL32684340 0.81 MAPT (0.48) MRGPRX4GAAMAPTRAB9ASMN1; SMN2
SCHEMBL30929977 0.79 SLC6A3 (0.49) MRGPRX4GAAMAPT
SCHEMBL7815690 0.77 PLAU (0.71) PLAUERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070867-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-12 US disclosed
WO-2024115460-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070867-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS CBR1, CBR3, SCO2 MRGPRX4 1763/4885PLAU 4680/4885ERN1 2782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.