SCHEMBL30929972

SCHEMBL30929972

COC(=O)c1ccc2cc(COc3ccc4cc(-c5ccccc5)ccc4c3-c3c(OCc4ccc5cc(C(=O)OC)ccc5c4)ccc4cc(-c5ccccc5)ccc34)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 2/20 0.49
CYP19A1 P11511 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48
PLAU P00749 7/20 0.47
NR1H4 Q96RI1 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
ERN1 O75460 1/20 0.44
EGFR P00533 1/20 0.44
PLAT P00750 2/20 0.43
PLG P00747 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
LCK P06239 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30929974 0.95 PLAU (0.47) SMPD1CYP19A1CYP11B1CYP11B2PLAU
SCHEMBL30929976 0.94 SMPD1 (0.54) SMPD1CYP19A1CYP11B1CYP11B2NR1H4
SCHEMBL30929975 0.92 MRGPRX4 (0.56) PLAUMRGPRX4ERN1PPARD
SCHEMBL30929964 0.88 MAPT (0.49) SMPD1PLAUMAPTRAB9A
SCHEMBL32684340 0.87 MAPT (0.48) MRGPRX4MAPTRAB9A
SCHEMBL30929969 0.86 MRGPRX4 (0.51) PLAUMRGPRX4ERN1MAPTRAB9A
SCHEMBL32684052 0.84 MAPT (0.46) MRGPRX4MAPTRAB9A
SCHEMBL2311608 0.80 CYP19A1 (0.69) CYP19A1CYP11B1CYP11B2PLAUEGFR
SCHEMBL30929949 0.78 MAPT (0.55) MAPTRAB9A
SCHEMBL30929950 0.78 FDPS (0.46) SMPD1ERN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115460-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-06-06 WO disclosed