Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.51 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 9/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14670585 | 1.00 | USP1 (0.51) | USP1WDR48LMNAHPGDSMN1; SMN2 | |
| SCHEMBL14670663 | 1.00 | USP1 (0.51) | USP1WDR48LMNAHPGDSMN1; SMN2 | |
| SCHEMBL29608562 | 0.88 | CRHR1 (0.46) | USP1WDR48LMNAEGFRCRHR1 | |
| SCHEMBL28721300 | 0.88 | CRHR1 (0.46) | USP1WDR48LMNAEGFRCRHR1 | |
| SCHEMBL27717397 | 0.87 | NTRK1 (0.48) | USP1WDR48LMNAHPGDSMN1; SMN2 | |
| SCHEMBL14670573 | 0.86 | EGFR (0.46) | LMNAHPGDSMN1; SMN2EGFRCCNC | |
| SCHEMBL14662047 | 0.86 | EGFR (0.46) | LMNAHPGDSMN1; SMN2EGFRCCNC | |
| SCHEMBL14662045 | 0.86 | EGFR (0.46) | LMNAHPGDSMN1; SMN2EGFRCCNC | |
| SCHEMBL14670671 | 0.85 | USP1 (0.51) | USP1WDR48LMNAHPGDSMN1; SMN2 | |
| SCHEMBL14670658 | 0.84 | EGFR (0.45) | LMNAHPGDSMN1; SMN2EGFRCCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084892-A | Compounds useful as HPK1 inhibitors | 深圳福沃药业有限公司 | 2024-05-28 | — | — | CN | disclosed |