Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 6/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29891088 | 1.00 | PGK1 (0.44) | PGK1FURINGPR119ADKMGLL | |
| SCHEMBL21564440 | 1.00 | PGK1 (0.44) | PGK1FURINGPR119ADKMGLL | |
| SCHEMBL29891361 | 0.95 | FURIN (0.48) | PGK1FURINGPR119ADKCKS1B | |
| SCHEMBL21551215 | 0.95 | FURIN (0.48) | PGK1FURINGPR119ADKCKS1B | |
| SCHEMBL30931809 | 0.95 | FURIN (0.48) | PGK1FURINGPR119ADKCKS1B | |
| SCHEMBL21551516 | 0.91 | GPR119 (0.42) | PGK1FURINGPR119CKS1BSKP1 | |
| SCHEMBL30931835 | 0.91 | GPR119 (0.42) | PGK1FURINGPR119CKS1BSKP1 | |
| SCHEMBL29890753 | 0.91 | GPR119 (0.42) | PGK1FURINGPR119CKS1BSKP1 | |
| SCHEMBL30931850 | 0.90 | GPR119 (0.45) | FURINGPR119 | |
| SCHEMBL21551237 | 0.90 | GPR119 (0.45) | FURINGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |