Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356986 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL5208634 | 0.84 | MAPT (0.70) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL4888533 | 0.84 | MAPT (0.75) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL17084253 | 0.84 | MEN1 (0.87) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| Acetic Acid SCHEMBL27563712 | 0.82 | MEN1 (0.63) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL6138093 | 0.82 | MAPT (0.58) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL651726 | 0.82 | MAPT (0.64) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL11777113 | 0.82 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL24756290 | 0.81 | MAPT (0.76) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL14820333 | 0.81 | SMN1; SMN2 (0.66) | MAPTMEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |