Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208634 | 0.85 | MAPT (0.70) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL17084253 | 0.85 | MEN1 (0.87) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL356986 | 0.84 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL11777113 | 0.84 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL30933151 | 0.84 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7748130 | 0.83 | SMN1; SMN2 (0.71) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL24756290 | 0.82 | MAPT (0.76) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL14820333 | 0.82 | SMN1; SMN2 (0.66) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7611935 | 0.82 | MEN1 (0.76) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL30926970 | 0.82 | SMN1; SMN2 (0.74) | MAPTMEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| CN-107001246-B | Naphthyl acrylates as writing monomers for photopolymers | 科思创德国股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-20080249075-A1 | C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249075-A1 | C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds | HSD17B11, CYP19A1, ESRRA | MAPT 4695/4885MEN1 639/4885KMT2A 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.