SCHEMBL5208634

SCHEMBL5208634

CSc1cccc(NC(C)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.70
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
SMN1; SMN2 Q16637 3/20 0.70
POLB P06746 2/20 0.70
HSD17B10 Q99714 2/20 0.70
TP53 P04637 1/20 0.70
MAPK1 P28482 1/20 0.70
CYP1A2 P05177 3/20 0.62
CYP3A4 P08684 2/20 0.62
CYP2D6 P10635 2/20 0.62
CYP2C9 P11712 2/20 0.62
CYP2C19 P33261 2/20 0.62
ALDH1A1 P00352 4/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
HPGD P15428 1/20 0.59
RECQL P46063 1/20 0.59
GRM4 Q14833 1/20 0.59
ALPG P10696 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13836493 0.87 ALDH1A1 (0.61) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL17324145 0.87 ALDH1A1 (0.61) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL4888533 0.85 MAPT (0.75) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL17084253 0.85 MEN1 (0.87) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL11679178 0.84 MEN1 (0.77) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL356986 0.84 MAPT (0.68) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL21415471 0.84 ALDH1A1 (0.58) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL11777113 0.84 MAPT (0.68) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL4219569 0.84 ALDH1A1 (0.58) MAPTMEN1KMT2ASMN1; SMN2POLB
SCHEMBL30933151 0.84 MAPT (0.68) MAPTMEN1KMT2ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112886052-A Composite electrolyte material, preparation method thereof and quasi-solid battery 昆山宝创新能源科技有限公司 2021-06-01 CN claimed
CN-113474156-B Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2022-04-29 CN disclosed
CN-113474156-A Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2021-10-01 CN disclosed
CN-112886052-A Composite electrolyte material, preparation method thereof and quasi-solid battery 昆山宝创新能源科技有限公司 2021-06-01 CN disclosed
US-9856254-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-01-02 US disclosed
US-9611273-B2 Trioxane thioacetal monomers and dimers and methods of use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2017-04-04 US disclosed
US-20160280707-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2016-09-29 US disclosed
US-20160280707-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2016-09-29 US disclosed
US-9365567-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-14 US disclosed
US-9365567-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-14 US disclosed
US-4677202-A Quaternized 2,1,4-benzoxatellurazinium and 2,1,4-naphthoxatellurazinium salt derivitives EASTMAN KODAK COMPANY (US) 1987-06-30 US disclosed
US-4661438-A Quaternized tellurium salt fog inhibiting agents for silver halide photography EASTMAN KODAK COMPANY (US) 1987-04-28 US disclosed
EP-0201201-A2 Amido substituted divalent chalcogenide fog inhibiting agents for silver halide photography EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-11-12 EP disclosed
EP-0198634-A2 Quaternized tellurium salt fog inhibiting agents for silver halide photography EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-10-22 EP disclosed
EP-0192464-A2 Tellurium salt fog inhibiting agents for silver halide photography EASTMAN KODAK COMPANY (US) 1986-08-27 EP disclosed
EP-0192466-A2 Novel chalcogen heterocycles, processes for their preparation, and articles containing such heterocycles EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-08-27 EP disclosed
US-4581330-A AROMATIC OXATELLURAZINIUM SALTS EASTMAN KODAK COMPANY (US) 1986-04-08 US disclosed
US-4576905-A Photographically useful chalcogenazoles, chalcogenazolines, and chalcogenazolinium and chalcogenazolium salts EASTMAN KODAK COMPANY (US) 1986-03-18 US disclosed
EP-0138362-A2 Photographic materials containing chalcogenazoles, chalcogenazolines and chalcogenazolinium and chalcogenazolium salts EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-24 EP disclosed
EP-0136847-A2 Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280707-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES IL2, IFNG, IRF3 MAPT 4571/4885MEN1 3720/4885KMT2A 2789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.