Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24757849 | 1.00 | MAPK1 (0.38) | MAPK1CYP11B2ALDH1A1KDM4EMEN1 | |
| SCHEMBL16679465 | 0.77 | MAPK1 (0.42) | MAPK1CYP11B2KMT2A | |
| SCHEMBL14228280 | 0.77 | KDM4E (0.38) | CYP11B2ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL16680561 | 0.74 | MAPK1 (0.38) | MAPK1KDM4ELMNAKMT2ASMN1; SMN2 | |
| SCHEMBL26548130 | 0.74 | SMN1; SMN2 (0.38) | MAPK1MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL19984649 | 0.73 | CYP11B2 (0.41) | CYP11B2ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL24534027 | 0.73 | CYP11B2 (0.46) | CYP11B2ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL2713555 | 0.69 | CYP11B2 (0.41) | MAPK1CYP11B2IKBKETBK1 | |
| SCHEMBL23623126 | 0.67 | HDAC4 (0.36) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL16678945 | 0.67 | MAPK1 (0.42) | MAPK1CYP11B2KMT2AIKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |