Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.98 |
| ▸ | POLB | P06746 | 2/20 | 0.98 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | MERTK | Q12866 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PGK1 | P00558 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282654 | 1.00 | RAD52 (1.00) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL18282544 | 0.95 | RAD52 (1.00) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL10031967 | 0.88 | RAD52 (0.98) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL18282619 | 0.84 | RAD52 (1.00) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL30933352 | 0.84 | RAD52 (1.00) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL26646013 | 0.83 | MERTK (0.87) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL26645968 | 0.83 | TAAR1 (0.98) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL10358560 | 0.81 | GBA1 (0.77) | RAD52KMT2APOLBGBA1 | |
| SCHEMBL23747981 | 0.79 | SLC2A1 (0.66) | RAD52KMT2APOLBHTTUSP2 | |
| SCHEMBL30125191 | 0.78 | HTT (0.72) | RAD52KMT2APOLBHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199636-A1 | Inhibitors of RAD52 Recombination Protein and Methods Using Same | UNIV DREXEL (US) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199636-A1 | Inhibitors of RAD52 Recombination Protein and Methods Using Same | RAD52, RAD50, MRE11 | RAD52 1/4885KMT2A 590/4885POLB 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.