Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 8/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | MERTK | Q12866 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282619 | 1.00 | RAD52 (1.00) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL10031967 | 0.93 | RAD52 (0.98) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL18282544 | 0.89 | RAD52 (1.00) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL18282654 | 0.84 | RAD52 (1.00) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL30933262 | 0.84 | RAD52 (1.00) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL2583768 | 0.82 | RAD52 (0.71) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL8900319 | 0.79 | NPY5R (0.67) | RAD52HTTUSP2TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL8891019 | 0.78 | SLC2A1 (0.70) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL26645968 | 0.76 | TAAR1 (0.98) | RAD52HTTUSP2TSHRKMT2A | |
| SCHEMBL22633484 | 0.76 | TAAR1 (0.85) | RAD52HTTTSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199636-A1 | Inhibitors of RAD52 Recombination Protein and Methods Using Same | UNIV DREXEL (US) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199636-A1 | Inhibitors of RAD52 Recombination Protein and Methods Using Same | RAD52, RAD50, MRE11 | RAD52 1/4885HTT 2986/4885USP2 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.