SCHEMBL30933367

SCHEMBL30933367

COc1cc(C=CC(=O)c2c(O)c3ccccc3oc2=O)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 6/20 0.67
MAPT P10636 7/20 0.65
KMT2A Q03164 6/20 0.65
KDM4E B2RXH2 5/20 0.65
MEN1 O00255 4/20 0.65
RAB9A P51151 2/20 0.64
RECQL P46063 2/20 0.64
GPR55 Q9Y2T6 1/20 0.64
CYP1A2 P05177 2/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
LMNA P02545 2/20 0.59
CXCL12 P48061 2/20 0.57
PTGS1 P23219 1/20 0.57
PTGS2 P35354 1/20 0.57
ABCG2 Q9UNQ0 1/20 0.56
CYP3A4 P08684 1/20 0.55
HPGD P15428 1/20 0.55
MCL1 Q07820 1/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27349811 1.00 NQO1 (0.67) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL13100090 0.81 NQO1 (0.81) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL7757059 0.81 NQO1 (1.00) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL7757057 0.81 NQO1 (1.00) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL10362375 0.80 NQO1 (0.85) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL31419764 0.80 NQO1 (0.85) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL10362376 0.80 NQO1 (0.85) NQO1MAPTKMT2AKDM4EMEN1
SCHEMBL28245362 0.80 PTGS1 (0.64) MAPTKMT2AKDM4EMEN1RAB9A
SCHEMBL28245361 0.80 PTGS1 (0.64) MAPTKMT2AKDM4EMEN1RAB9A
SCHEMBL5801289 0.79 KMT2A (1.00) MAPTKMT2AKDM4EMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024129601-A1 COMPOUND EMBODIMENTS FOR MUSCLE MYOSIN INHIBITION AND METHODS OF MAKING AND USING THE SAME BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIV. OF NEVADA (US) 2024-06-20 WO disclosed