Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.59 |
| ▸ | KDM6B | O15054 | 6/20 | 0.59 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | KDM4A | O75164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116912 | 1.00 | KDM4C (0.59) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1027775 | 0.98 | KDM4C (0.57) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| Nitrous Acid SCHEMBL28552198 | 0.92 | KDM4C (0.52) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| SCHEMBL8687513 | 0.88 | TDP1 (0.54) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| SCHEMBL1027774 | 0.83 | GAA (0.45) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| SCHEMBL7533 | 0.83 | ROCK2 (0.58) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| SCHEMBL29574646 | 0.83 | ROCK2 (0.58) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL17143441 | 0.81 | ROCK2 (0.56) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| SCHEMBL826357 | 0.81 | MKNK1 (0.58) | KDM4CKDM6BKDM4DALDH1A1KDM4E | |
| SCHEMBL1891569 | 0.81 | ROCK2 (0.47) | KDM4CKDM6BKDM4DALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226914-A2 | MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF | SEPTERNA, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024112287-A1 | BENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BANOGLU ERDEN (TR) | 2024-05-30 | — | — | WO | disclosed |