Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM6B | O15054 | 2/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533 | 1.00 | ROCK2 (0.58) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL1942270 | 0.98 | ROCK2 (0.56) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL17143441 | 0.98 | ROCK2 (0.56) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| SCHEMBL8686759 | 0.88 | ROCK2 (0.47) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| SCHEMBL30465597 | 0.83 | ROCK2 (0.58) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| SCHEMBL116912 | 0.83 | KDM4C (0.59) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| SCHEMBL587010 | 0.83 | ROCK2 (0.58) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| SCHEMBL15514423 | 0.83 | ROCK2 (0.58) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| SCHEMBL30933589 | 0.83 | KDM4C (0.59) | ROCK2ROCK1KDM4CALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL2432397 | 0.81 | ROCK2 (0.56) | ROCK2ROCK1KDM4CALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| EP-3976608-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |