Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933560 | 0.87 | KIT (0.43) | TRPV1PARP1SMN1; SMN2NPC1LMNA | |
| SCHEMBL31343163 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1LMNAMAPTRAB9A | |
| SCHEMBL6793964 | 0.78 | PKM (0.57) | SMN1; SMN2NPC1RAB9ANTRK1NTRK2 | |
| SCHEMBL30933587 | 0.76 | NTRK1 (0.49) | SMN1; SMN2MAPTNTRK1NTRK2PKM | |
| SCHEMBL30341867 | 0.75 | PARP1 (0.54) | TRPV1PARP1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2564888 | 0.73 | BCAT2 (0.65) | PARP1SMN1; SMN2BCAT2 | |
| SCHEMBL1797890 | 0.73 | TRPV1 (0.70) | TRPV1PARP1 | |
| SCHEMBL1797892 | 0.73 | TRPV1 (0.70) | TRPV1PARP1 | |
| SCHEMBL8327709 | 0.73 | HDAC1 (0.53) | MAOBPPARG | |
| SCHEMBL23280145 | 0.73 | SRD5A2 (0.52) | SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025048759-A1 | BENZIMIDAZOLE DERIVATIVES AS MPGES-1 INHIBITORS | ICOSYN THERAPEUTICS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) | 2025-03-06 | — | — | WO | claimed |
| WO-2024112287-A1 | BENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BANOGLU ERDEN (TR) | 2024-05-30 | — | — | WO | claimed |