Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933694 | 0.99 | PRMT5 (0.47) | PRMT5WDR77POLBKDM4EMEN1 | |
| SCHEMBL30933867 | 0.78 | PRMT5 (0.53) | PRMT5WDR77MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL30933745 | 0.77 | PRMT5 (0.67) | PRMT5WDR77POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30933675 | 0.77 | PRMT5 (0.52) | PRMT5WDR77MEN1KMT2ATP53 | |
| SCHEMBL30933763 | 0.77 | STS (0.52) | KDM4ETP53 | |
| SCHEMBL30933773 | 0.76 | CYP2D6 (0.56) | PRMT5WDR77POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30933667 | 0.75 | PRMT5 (0.47) | PRMT5WDR77MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL30933803 | 0.75 | CYP1A2 (0.58) | PRMT5WDR77POLBKDM4EMEN1 | |
| SCHEMBL30933875 | 0.74 | PRMT5 (0.46) | PRMT5WDR77MEN1KMT2ATP53 | |
| SCHEMBL20324364 | 0.73 | MEN1 (0.58) | PRMT5WDR77POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |