Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933801 | 0.90 | TACR1 (0.41) | TACR1HPGDSKCNH2CYP2D6EPHX2 | |
| SCHEMBL30933830 | 0.84 | MAPK8 (0.45) | NPBWR1MCHR1L3MBTL1CYP2D6POLB | |
| Hydrochloric Acid SCHEMBL30933670 | 0.81 | TACR1 (0.55) | TACR1NPBWR1MCHR1KCNH2CYP2D6 | |
| SCHEMBL30933652 | 0.79 | TACR1 (0.55) | TACR1NPBWR1MCHR1KCNH2CYP2D6 | |
| SCHEMBL30933703 | 0.78 | CYP1A2 (0.43) | NPBWR1MCHR1L3MBTL1CYP2D6ALDH1A1 | |
| SCHEMBL4258082 | 0.77 | ADRA2A (0.50) | MCHR1EPHX2KDM1AMAOB | |
| SCHEMBL4258087 | 0.77 | ADRA2A (0.50) | MCHR1EPHX2KDM1AMAOB | |
| SCHEMBL30933776 | 0.76 | CYP1A2 (0.44) | NPBWR1MCHR1L3MBTL1CYP2D6HTR2A | |
| SCHEMBL30933742 | 0.75 | KDM4E (0.46) | TACR1KCNH2EPHX2 | |
| SCHEMBL30933701 | 0.74 | MAPK8 (0.44) | HTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |