Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933705 | 0.99 | EP300 (0.48) | EP300TDP1MTNR1AMTNR1BHTR4 | |
| Hydrochloric Acid SCHEMBL30933650 | 0.85 | TACR1 (0.53) | EP300PRMT5WDR77TACR1CYP1A2 | |
| SCHEMBL30933924 | 0.84 | PRMT5 (0.42) | ALDH1A1PRMT5WDR77CYP1A2CYP2D6 | |
| SCHEMBL30933773 | 0.84 | CYP2D6 (0.56) | PRMT5WDR77CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL30933803 | 0.83 | CYP1A2 (0.58) | ALDH1A1PRMT5WDR77CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL30933664 | 0.83 | MAPK1 (0.44) | ALDH1A1PRMT5WDR77CYP1A2CYP2D6 | |
| SCHEMBL31507094 | 0.83 | APLNR (0.61) | EP300TDP1HTR4ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30933813 | 0.81 | CYP1A2 (0.43) | EP300ALDH1A1PRMT5WDR77TACR1 | |
| SCHEMBL30933867 | 0.79 | PRMT5 (0.53) | EP300HTR4PRMT5WDR77CYP1A2 | |
| Hydrochloric Acid SCHEMBL30933675 | 0.78 | PRMT5 (0.52) | EP300HTR4PRMT5WDR77CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |