Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24680477 | 0.76 | PARP10 (0.44) | KDM4E | |
| SCHEMBL12078315 | 0.76 | CDC7 (0.39) | CDC7KDM4E | |
| SCHEMBL30926385 | 0.76 | CDC7 (0.39) | CDC7KDM4E | |
| SCHEMBL30934959 | 0.75 | CDC7 (0.37) | CDC7KDM4EJAK2 | |
| SCHEMBL31426318 | 0.75 | CDC7 (0.39) | CDC7KDM4EJAK2 | |
| SCHEMBL30926169 | 0.74 | LPL (0.34) | CDC7JAK2 | |
| SCHEMBL1646761 | 0.71 | LPL (0.44) | JAK2BTK | |
| SCHEMBL25252454 | 0.70 | HSD17B1 (0.35) | JAK2BTK | |
| SCHEMBL4471407 | 0.69 | LPL (0.42) | JAK2BTK | |
| SCHEMBL25395984 | 0.68 | LPL (0.41) | JAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |