Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 4/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924440 | 0.83 | TMEM97 (0.49) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL2927270 | 0.83 | TMEM97 (0.49) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL3343083 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL31275430 | 0.80 | DGAT1 (0.51) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL27765923 | 0.79 | DGAT1 (0.51) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL26838419 | 0.79 | TMEM97 (0.59) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL25284100 | 0.78 | TMEM97 (0.47) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL3346723 | 0.76 | DGAT1 (0.54) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL29249951 | 0.76 | DGAT1 (0.54) | KMT2AALDH1A1NPC1LMNAGAA | |
| SCHEMBL4510569 | 0.75 | TMEM97 (0.58) | KMT2AALDH1A1NPC1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |