Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | BTK | Q06187 | 3/20 | 0.58 |
| ▸ | JAK3 | P52333 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TGM1 | P22735 | 1/20 | 0.46 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235432 | 1.00 | TGM2 (0.61) | TGM2TRPV1BTKJAK3JAK2 | |
| SCHEMBL29246639 | 0.98 | TGM2 (0.59) | TGM2TRPV1BTKJAK3JAK2 | |
| Acrylamide SCHEMBL22206248 | 0.94 | TGM2 (0.55) | TGM2TRPV1BTKJAK3JAK2 | |
| Acrylamide SCHEMBL30480310 | 0.94 | TGM2 (0.55) | TGM2TRPV1BTKJAK3JAK2 | |
| SCHEMBL23199033 | 0.89 | TDP1 (0.54) | TGM2TRPV1BTKJAK3JAK2 | |
| SCHEMBL30480308 | 0.89 | TGM2 (0.50) | TGM2TRPV1BTKJAK3JAK2 | |
| SCHEMBL18100115 | 0.87 | TGM2 (0.58) | TGM2TRPV1BTKJAK3F13A1 | |
| SCHEMBL4103284 | 0.84 | TGM2 (0.76) | TGM2BTKJAK3F13A1LMNA | |
| SCHEMBL16193308 | 0.83 | TGM2 (0.54) | TGM2TRPV1BTKJAK3F13A1 | |
| SCHEMBL11349846 | 0.81 | TRPV1 (0.51) | TRPV1BTKNLRP3ESRRGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |