Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.32 |
| ▸ | ITGAV | P06756 | 8/20 | 0.32 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | STK26 | Q9P289 | 2/20 | 0.30 |
| ▸ | STK24 | Q9Y6E0 | 2/20 | 0.30 |
| ▸ | STK4 | Q13043 | 1/20 | 0.30 |
| ▸ | STK3 | Q13188 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600058 | 0.89 | NNMT (0.38) | NNMTTYRO3DYRK1BKDM4EGRM5 | |
| SCHEMBL13355389 | 0.78 | UHRF1 (0.43) | NNMTUHRF1MAPTITGB3ITGAV | |
| SCHEMBL24197697 | 0.75 | ITGAV (0.44) | NNMTUHRF1MAPTITGB3ITGAV | |
| SCHEMBL26013992 | 0.74 | NNMT (0.38) | NNMTUHRF1MAPTITGB3ITGAV | |
| SCHEMBL25468393 | 0.73 | UHRF1 (0.39) | NNMTUHRF1MAPTITGB3ITGAV | |
| SCHEMBL1810290 | 0.72 | ITGB3 (0.39) | NNMTUHRF1ITGB3ITGAVITGB6 | |
| SCHEMBL31000386 | 0.70 | NNMT (0.55) | NNMTUHRF1MAPTKDM4EGRM5 | |
| SCHEMBL30555417 | 0.70 | KDM4E (0.32) | TYRO3DYRK1BKDM4E | |
| SCHEMBL31393519 | 0.70 | KDM4E (0.32) | MAPTTYRO3DYRK1BKDM4E | |
| SCHEMBL19033509 | 0.70 | ITGAV (0.35) | NNMTUHRF1MAPTITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |