Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.43 |
| ▸ | EGFR | P00533 | 14/20 | 0.43 |
| ▸ | ITK | Q08881 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | TEC | P42680 | 1/20 | 0.43 |
| ▸ | TXK | P42681 | 1/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | CD69 | Q07108 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30935094 | 0.85 | EGFR (0.42) | BTKEGFRITKTXKJAK3 | |
| SCHEMBL30935137 | 0.82 | TGM2 (0.47) | BTKEGFRITKJAK2LYN | |
| SCHEMBL28310779 | 0.78 | EGFR (0.58) | BTKEGFRITKJAK2LYN | |
| SCHEMBL28310060 | 0.77 | TGM2 (0.67) | BTKEGFRITKJAK2LYN | |
| SCHEMBL30934987 | 0.75 | EGFR (0.43) | BTKEGFRITKJAK2JAK3 | |
| SCHEMBL30935107 | 0.75 | EGFR (0.40) | BTKEGFRITKJAK2LYN | |
| SCHEMBL30935182 | 0.74 | EGFR (0.48) | EGFRITK | |
| SCHEMBL30935106 | 0.74 | TGM2 (0.53) | BTKEGFRITKTGM2 | |
| SCHEMBL28463718 | 0.71 | EGFR (0.63) | BTKEGFRITKJAK2LYN | |
| SCHEMBL30935247 | 0.71 | TGM2 (0.53) | BTKEGFRITKJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |