Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936604 | 0.89 | ALDH1A1 (0.49) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL1136265 | 0.83 | HTT (0.56) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL16538184 | 0.82 | HTT (0.54) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL2773641 | 0.80 | LMNA (0.67) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL27671287 | 0.80 | ALDH1A1 (0.53) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL30936695 | 0.78 | LMNA (0.49) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL6819450 | 0.78 | ALDH1A1 (0.65) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9909358 | 0.77 | NPC1 (0.48) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL5242389 | 0.77 | LMNA (0.50) | HTTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL15618541 | 0.77 | HTT (0.64) | HTTLMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608389-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | Nine Square Therapeutics Corporation (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024092235-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2024-05-02 | — | — | WO | disclosed |